Study of the Effects of Naturally Occurring Radioactive Materials on Blood Indices in Blood’s Rats

Abdelgawad, Mahmoud H.; Awd, Misara; Tohamy, Khairy M

doi:10.21608/ejbbe.2019.7930.1024

Study of the Effects of Naturally Occurring Radioactive Materials on Blood Indices in Blood’s Rats

Document Type : Original Article

Authors

¹ Biophysics Branch, Physics Department, Faculty of Science, Al-Azhar University (Boys), Cairo, Egypt.

² Physics Department, Biophysics Branch, Faculty of Science, Al-Azhar University (Boys), Cairo, Egypt.

10.21608/ejbbe.2019.7930.1024

Abstract

TO UNDERSTAND the toxicity and the potential role of naturally occurring radioactive materials (NORM) as risk factors on rat’s blood characteristics. These materials cover both naturally occurring and man-made or artificial sources. The most common material is Radon, which results from naturally-occurring 232Th and 238U and serially passing as isotopes through a number of decays till a stable isotope evolves. The aim of this study was To investigate the potential effects and the oxidative damage caused by gamma radiation emitted from naturally occurring radioactive materials with low dose levels on the blood of male rats. Groups of adult male rats were classified and exposed to different doses result from NORM. The expected changes the changes in the concentration of total Protein, Albumin, and Globulin according to the exposure were measured, in addition to the change in some hematological parameters. The results indicated that all irradiated groups showed significant decreasing in the concentration of Total Protein, Total Albumin, Total Globulin, Albumin / Globulin Ratio, the Platelets numbers (PLTs) and platelets Volume (MPV) Globulin and Albumin / Globulin Ratio and a significant decreasing in the Platelets numbers and volumes (PLTs), (MPV)At the same time, the results showed increases in the PLTs/Lymphocytes ratio compared with the control group. The results established that the exposure to TENORM dose has some deleterious effects as observed in Albumin and Lymphocytes elevation. In conclusion, the naturally occurring radioactive materials have a significant effect on the blood system in male rats.

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